COVID-19: Drugs in Development

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COVID-19: Drugs in Development

The COVID-19 outbreak, which started in December 2019 in Wuhan City, China, was declared a "Public Health Emergency of International Concern" by the WHO on January 30, 2020. The outbreak was characterized as a pandemic on March 11, 2020.

Currently, there are no drugs to treat COVID-19, caused by the novel coronavirus SARS-CoV-2.

Listed below are companies that are in the race to find a treatment or vaccine for the novel coronavirus.

Company Name Drug Current Stage Next Milestone Collaboration Last Updated

Incyte Corporation

INCY

 OLUMIANT

Phase 3 trial of Olumiant in hospitalized participants with COVID-19, dubbed COV-BARRIER

 Results expected in December 2020 Lilly 10/19/2020

Incyte Corporation

INCY

 Jakafi Phase 3 trial of Jakafi in patients with COVID-19-associated Acute Respiratory Distress Syndrome who require mechanical ventilation (RUXCOVID-DEVENT)     10/19/2020

Relief Therapeutics Holding AG

(RLFTF. OB)

 RLF-100 US Phase 2b/3 clinical trials of RLF-100 in respiratory deficiency due to COVID-19 Topline data expected in Q4, 2020   10/13/2020
Altimmune Inc. AdCOVID Intranasal Covid-19 vaccine Positive results from the preclinical studies of AdCOVID announced on Jul.13 Phase 1 clinical trial of AdCOVID in Q4 2020 Vigene Biosciences, DynPort Vaccine Co. 10/13/2020
HUMANIGEN, INC Lenzilumab Phase III trial of Lenzilumab in severe and critical COVID-19 patients Topline data expected in Q4, 2020   10/09/2020
Hepion Pharmaceuticals, Inc. CRV431 Preclinical stage   National Institute of Allergy and Infectious Diseases 10/09/2020

Information and calendar provided by RTTnews.com.

For comments and feedback contact: editorial@rttnews.com

Article written by an RTT News Staff Writer, and posted on the RTT News.com website.

Article reposted on Markethive by Jeffrey Sloe

Bitcoin Whales Stomp Crypto Market Send Exchanges Into Danger Zone

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Bitcoin Whales Stomp Crypto Market, Send Exchanges Into “Danger Zone”

By Adrian Klent – November 6, 2020

New on-chain analytical data from CryptoQuant is hinting that Bitcoin whales have stomped the market. Usually, the arrival of Bitcoin whales is received with skepticism and this time is no different, especially as the Bitcoin rally has surged increasingly over the past week, to now keep Bitcoin up at the higher ends of $15,000. Particularly $15,633 at the time of this writing.

As we all know, cryptocurrency exchanges are the backbone of the market and any threat to the market could potentially affect Bitcoin’s price point and according to this new analysis, spot exchanges are entering a “danger zone.”

It appears that the arrival of these whales, which have been excessively depositing Bitcoin into the market, had an effect on the exchange inflow mean that is now above 2BTC, ($30,000+ according to the current market price), this is said to be a very critical area for the market.

Over the past week, analysts have been critiquing Bitcoin’s bull run, and some have speculated that the pump is coming from whales who may not be able to sustain the market. With this analysis establishing that there’s indeed a pump from the big dogs, Bitcoin whales and traders might hold onto their Bitcoins until the price point hits the peak and sell once investors are forced to pull out of the market if and when the bulls get hit by a strong price rejection.

In an updated tweet, the analyst is stating that the anticipated dump may not be as severe afterall, instead the analyst rephrases and says that:

“We might have small $BTC drops but In the long run, we’re safe from mass-dumping.

The 90-day moving average of the Exchange Whale Ratio is still low.”

Adding that he’s still bullish on Bitcoin, the analyst reaffirmed that it was necessary to try to avoid a whale dump regardless.

Whale dumps usually hit the Bitcoin market hard and most times lead to a bear market. At this point, the whales will begin to cash out and the long term players will be left to deal with the losses.

Again, as analysts have advised on several occasions, buying the dip is more than likely to pay off. However, the big picture which is Bitcoin has been in the spotlight for a while now. After making a sharp market climb to $15,000, it seems like Bitcoin might only need another 24hours or less to make a price jump to $16,000.

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DISCLAIMER

The views expressed in the article are wholly those of the author and do not represent those of, nor should they be attributed to, ZyCrypto. This article is not meant to give financial advice. Please carry out your own research before investing in any of the various cryptocurrencies available.

The original article written by Adrian Klent and posted on ZyCrypto.com.

Article reposted on Markethive by Jeffrey Sloe

Justice Department seizes 1 billion in recently moved Silk Road crypto

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Justice Department seizes $1 billion in recently moved Silk Road crypto

The move follows widespread crackdowns by the DoJ on crypto.


Image courtesy of CoinTelegraph

            NOV 05, 2020

In a filing on Thursday, the United States Department of Justice asked to seize $1 billion from an unnamed hacker.

Specifically, the DoJ is asking the court of the Northern District of California to lock down on "approximately 69,370.22491543 Bitcoin (BTC), Bitcoin Gold (BTG), Bitcoin SV (BSV), Bitcoin Cash (BCH), obtained from 1HQ3Go3ggs8pFnXuHVHRytPCq5fGG8Hbh."

The court document did not identify the person behind the wallet, instead referring to them as "Individual X," but it does allege that they managed to hack Silk Road and steal the crypto, much to the chagrin of Ross Ulbricht. The hacker apparently already agreed to sign over the funds as of Monday, which is likely why those funds changed hands for the first time in five years this week.

The value of those funds today makes this the largest crypto seizure in history.

The DoJ has gotten much more active in crypto in the past month. At the beginning of October, the agency released its framework for crypto enforcement, which some have called a harbinger of a major crackdown.

Meanwhile, the DoJ has profited considerably by auctioning off confiscated crypto.

The DoJ had not responded to Cointelegraph's request for comment as of publication time.

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Original article posted on the CoinTelegraph.com site, by Johann Polecsak.

Article re-posted on Markethive by Jeffrey Sloe

Bitcoin Inches Closer to 15k as BTC Dominance Decimates Altcoins

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Bitcoin Inches Closer to $15k as BTC Dominance Decimates Altcoins

John P. Njui   •   BITCOIN (BTC) NEWS   •   NOVEMBER 5, 2020

Summary:

  • Bitcoin has continued on its bullish climb above $14k
  • BTC just hit a 2020 high of $14,785
  • Such levels were last seen during the 2017/2018 bull run
  • Bitcoin market cap dominance has continued to increase at the expense of altcoins

As the world’s focus is glued to the 2020 US Elections, Bitcoin is making major moves last seen during the 2017/2018 bull season. At the time of writing, Bitcoin is trading at $14,750 – Binance rate -and after printing a yearly high of $14,785. Bitcoin’s current push up could very well be the beginning of the journey to $20k and possibly a new all-time high value.

What the Bitcoin Chart Says

A quick glance at the daily BTC/USDT chart reveals that Bitcoin is in parabolic territory similar to that witnessed in December of 2017 and May 2019.


Chart courtesy of Tradingview.com (Click image for larger view)

In terms of resistances, Bitcoin has very few of them ahead as it attempts to break the December 2017 all-time high value at $20k. The obvious resistances lie at the following levels last witnessed in 2017.

  • $14,750
  • $15,000
  • $15,500
  • $15,720
  • $16,500
  • $17,125
  • $17,490
  • $18,050

Also from the daily chart shared above, it can be observed that Bitcoin’s price is very much above the 50-day, 100-day and 200-day moving averages. The daily trade volume is also in the green, with the daily MACD exhibiting an overbought situation. The daily MFI is also considerably high at 67.2.

Bitcoin Continues to Dominate at the Expanse of Altcoins

However, the current overbought scenario that Bitcoin is exhibiting might not mean much given that FOMO might already be in play for BTC. A good way of gauging how much capital is invested in Bitcoin is the BTC market cap dominance chart which clearly shows an increased interest in trading the digital asset.

A while back, it was pointed out that if the Bitcoin dominance exceeded 63%, altcoins would continue to suffer in the crypto markets. Revisiting the same dominance chart reveals that Bitcoin’s dominance is currently 65.89. What this means, is that the price of altcoins will continue to suffer as this value continues to increase.


Bitcoin dominance chart courtesy of Tradingview.com< (Click image for larger view)

Additionally, and given the continual institutional interest in Bitcoin, high chances are that BTC continues to be the fan-favorite of this category of investors through the rest of 2020 and possibly the first two quarters of 2021. As a result, altcoins led by Ethereum (ETH), will have to wait till the focus is away from Bitcoin for them to thrive.

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Original article posted on the EthereumWorldNews.com site, by John P. Njui.

Article re-posted on Markethive by Jeffrey Sloe

Bitcoin Smacks Three of America’s Biggest Finance Firms to Sit at First Place in Market Valuation

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Bitcoin Smacks Three of America’s Biggest Finance Firms to Sit at First Place in Market Valuation

By Brenda Ngari – November 4, 2020

Bitcoin’s evolution as an asset of great value has been reflected many times in the swiftness at which the asset has surpassed a large number of already existing firms in the financial industry. Against other assets that have taken the title as “store of value,’ Bitcoin has also shown immense strength in adding and retaining value faster than these assets.

And as this pattern continues, some industry players in the cryptocurrency landscape have taken out time to point out the staggering difference in Bitcoin’s value as an asset, but this time, against some of the world’s leading firms.

Bitcoin has effortlessly dismounted America’s leading finance firms

The analytic comparison made by one of the popular members of the cryptocurrency ecosystem Ran Neuner enlists JP Morgan Chase, Bank of America, Wells Fargo, and Citibank – four of America’s leading investment and financial service giants, all of which are have existed at least 60 years before Bitcoin’s inception. Interestingly, Bitcoin has managed to take first place as the most valued asset against three of these firms in only just 12 years of its creation.

Bitcoin could still easily unseat JPMorgan in a few years

JPMorgan, the only firm to bypass Bitcoin with $41 billion could still swap positions with Bitcoin in a few years’ time, given that Bitcoin’s price maturation process is more consistent. This draws back to factors like volatility and adoption, all of which have surged by each year.

Investment interest in Bitcoin which has now moved to see investors from other markets turn to Bitcoin as the substitute asset became a booming channel this year when the American economy had to deal with yet another recession. The global influx of institutional investment from leading firms and investors into the market could simultaneously jack up Bitcoin’s price value.

Circulating supply, which is the second metric used in measuring Bitcoin’s market cap will increase as mining activities intensify, thereby acting as another boost for Bitcoin’s market cap. However, it is important to note that Bitcoin’s market capitalization is not the most accurate metric for calculating its value.

Ironically, all the aforementioned firms have all bought into cryptocurrencies. JPMorgan has begun accepting Bitcoin for banking services. Earlier this year, news broke that the Bank of America was also considering cryptocurrencies like Bitcoin, Ethereum, and Bitcoin cash as equivalents for crypto-related transactions.

Clearly, Bitcoin’s usage is increasing and banks have no choice but to create policies and models that forces them to become crypto-inclusive. In the long run, the amplification of Bitcoin’s dominance will continue to be fueled by traditional firms.

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DISCLAIMER

The views expressed in the article are wholly those of the author and do not represent those of, nor should they be attributed to, ZyCrypto. This article is not meant to give financial advice. Please carry out your own research before investing in any of the various cryptocurrencies available.

The original article written by Brenda Ngari and posted on ZyCrypto.com.

Article reposted on Markethive by Jeffrey Sloe

Verizon Implements Blockchain-powered News Release Verification

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Verizon Implements Blockchain-powered News Release Verification

By RTTNews Staff Writer | Published: 11/3/2020 9:23 AM ET

Verizon is implementing a blockchain-verified record of changes to its news releases using its 'Full Transparency' initiative. It has the potential to change the way companies communicate to their audiences.

The Full Transparency initiative is a proof of concept built with open-source blockchain technology in partnership with Huge, MadNetwork and AdLedger. The blockchain-based, open-source newsroom product is designed to raise the bar for corporate accountability.

Full Transparency is expected to transform how the Verizon Corporate Newsroom publishes news releases by providing an authoritative record of changes to public communications.

All official news releases published to the Verizon Newsroom that incorporate Full Transparency will be secured and bound using cryptographic principles, so that subsequent changes can be tracked on the blockchain ledger and contextualized. All details and changes are recorded and stored with their own unique hash code and becomes a permanent part of the chain.

A blockchain is a shared ledger or record book where all relevant details about a content record are permanently logged and any changes rigorously tracked. Once information is recorded in the shared ledger, it's almost impossible to reverse or change it.

The lack of transparency has the potential to undercut corporate credibility, particularly for news releases from a publicly traded company. Nearly 60% of consumers globally believe that the media they consume is contaminated with untrustworthy information, according to the 2020 Edelman Trust Barometer.

Full Transparency will help change the way corporate newsrooms provide visibility to their readers and hold themselves accountable for what they communicate to the public.

The Full Transparency initiative is an extension of Citizen Verizon, a responsible business plan that drives economic, environmental and social advancement by promoting technology as a tool to improve communities, education and the workforce.

The initiative will help combat the spread of misinformation and creates a trustworthy, authoritative source for confirming company information. It documents all text changes made to the official news releases and all details are timestamped, making them easily verifiable.

This proof of concept is intended to convey a level of transparency that's unprecedented from a corporate newsroom. Verizon intends to help other organizations build trust and transparency through technology to bring more credibility to their publishing model.

For comments and feedback contact: editorial@rttnews.com

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Article written by an RTT News Staff Writer, and posted on the RTT News.com website.

Article reposted on Markethive by Jeffrey Sloe

ChainLink LINK and REN 2 Tokens to Escape Octoberamp8217s DeFi Correction

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ChainLink (LINK) and REN, 2 Tokens to Escape October’s DeFi Correction

John P. Njui   •   DEFI • CHAINLINK (LINK) NEWS   •   NOVEMBER 3, 2020

Summary:

  • Majority of known DeFi tokens have continued to lose value in the crypto markets
  • ChainLink (LINK) and REN are two DeFi tokens to post gains in October

The DeFi industry is currently experiencing what looks like a cooldown after an impressive run in Q3 of 2020. The cooldown has been accompanied by a significant drop in the value of prominent DeFi tokens such as Yearn Finance (YFI), Compound Finance (COMP), Curve Finance (CRV), just to name a few.

ChainLink (LINK) and REN, 2 DeFi Tokens With Gains in October

The performance of the top 10 DeFi tokens in the month of October was analyzed by the team at CryptoRank Platform who then concluded that only ChainLink (LINK) and Ren (REN) posted significant gains last month. According to CryptoRank, LINK and REN grew by 13.7% and 12.2% respectively. However, other prominent DeFi tokens continued with their losing streak in the crypto markets as highlighted in the tweet below by CryptoRank Platform.

More Crypto Projects Continue to Integrate ChainLink

Also in the month of October, 29 crypto-related projects integrated ChainLink technology bringing the total to 315 since the project was launched in 2017. Of this amount, 98 DeFi projects are currently using ChainLink to power their protocols. This data was collected and aggregated by @TheLinkMarine1 via the following tweet.

ChainLink’s Price is Testing the $10 Support

In terms of market value, ChainLink was also hard hit by yesterday’s crypto wide correction that saw LINK drop from $11.60 to as low as $9.94 – Binance rate. At the time of writing, ChainLink is trading above the crucial $10 psychological price area as the US elections kick-off today amidst plenty of anxiety in the traditional stock markets.

Yesterday’s volatility in the crypto markets was been linked to the Presidential Elections as well as a new wave of COVID19 infections in Europe that has resulted in lockdowns in France, Portugal and the UK. This means that the DeFi token correction will continue this week with the possibility of ChainLink retesting the $10 price area.

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Original article posted on the EthereumWorldNews.com site, by John P. Njui.

Article re-posted on Markethive by Jeffrey Sloe

Ethereum Holders Sent 8170 ETH to Crypto Exchanges Before Dip to 370

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Ethereum Holders Sent 8,170 ETH to Crypto Exchanges Before Dip to $370

John P. Njui   •   ETHEREUM (ETH) NEWS   •   NOVEMBER 3, 2020

Summary:

  • Crypto exchanges experienced an inflow of 8,170 ETH before yesterday’s dip to $370
  • This translates to around $3.1 Million using an Ethereum rate of $380
  • Of this amount 4,000 ETH was deposited to Binance before the brief meltdown
  • Selling of Ethereum could indicate buying exhaustion and a correction in the pipeline for ETH

This week kicked off on a tumultuous note in the crypto markets due to the two events of a US presidential elections today, and the rise of COVID19 cases in Europe that is causing further lockdowns. Early Monday saw the price of Ethereum drop from $404 to $370 in less than 6 hours.

Ethereum Holders Sent 8,170 ETH to Crypto Exchanges Before Dip

According to the team at CryptoQuant, approximately 8,170 ETH was sent to crypto exchanges before the dip. This translates to roughly $3.1 Million using Ethereum’s current price of $380. The team at CryptoQuant further shared their observation of the inflow of Ethereum into exchanges via the following tweet.

Also worth mentioning is that 4,000 ETH of this amount was sent to Binance 20 minutes before Ethereum took a brief nosedive in the crypto markets. This event was captured by the team at CoinMetrics as can be seen in the following tweet.

ETH Inflows Could Hint of a Local Top for Ethereum

The selling of Ethereum begun around the $400 price zone. This could signify that this price area was the last region that some ETH investors could sell their bags at a profit. Additionally, it could be the first sign of exhaustion for Ethereum at least for the month of November.


(Click image for larger view)

Further checking the daily ETH/USDT chart above, Ethereum could be in the midst of printing a bear flag that could result in the retest of several support zones above $300. They include those found at $365, $336, $320 and $309.

Also from the chart, the following can be observed.

  • The 50-day moving average is providing a level of support at the $370 price area
  • The 200-day MA is providing adequate support at the $300 price area
  • Failure of the aforementioned support zones could lead to Ethereum dropping to as low as $250
  • Trade volume is in the red with the daily MACD confirming bearishness for Ethereum
  • The daily MFI and RSI are also hinting at a correction at values of 58 and 46 respectively

Conclusion

Summing it up, Ethereum holders transferred 8,170 ETH to crypto exchanges before yesterday’s drop from $400 to $370. The transfer and subsequent selling could hint of bullish exhaustion for Ethereum and could open the doors for a correction for the better part of November.

As with all analyses of Ethereum, traders and investors are advised to use adequate stop losses when trading ETH on the various derivatives platforms.

 

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Original article posted on the EthereumWorldNews.com site, by John P. Njui.

Article re-posted on Markethive by Jeffrey Sloe

SEC votes to simplify exempt offering rules for securities

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SEC votes to simplify exempt offering rules for securities

"While each component in this patchwork system makes some sense in isolation, collectively, there is substantial room for improvement."


Image courtesy of CoinTelegraph

            NOV 02, 2020

The United States Securities and Exchange Commission voted to amend a set of rules to simplify and improve the "overly complex" procedures for exempt securities offerings.

According to an announcement Monday from the SEC, the proposed changes aim to "harmonize, simplify, and improve" the existing "overly complex" framework to make it easier for companies to conduct offerings while still protecting investors. The regulatory body stated that the amendments would "address gaps and complexities" in the current exempt-offering framework, facilitating access to investment opportunities for investors and to capital for securities issuers.

“For many small and medium-sized business, our exempt offering framework is the only viable channel for raising capital," said SEC Chairman Jay Clayton. "These businesses and their prospective investors must navigate a system of multiple exemptions and safe harbors, each with different requirements. While each component in this patchwork system makes some sense in isolation, collectively, there is substantial room for improvement."

Many of these attempts at improvement include the SEC voting to raise the maximum offering amount under Tier 2 of Regulation A from $50 million to $75 million for initial sales — which includes many token offerings — and from $15 million to $22.5 million for secondary sales. Likewise, the commission would expand the maximum offering amount for sales under the Regulation D framework from $5 million to $10 million.

The SEC also voted to change its Regulation Crowdfunding offering guidelines, raising the limit from $1.07 million to $5 million, and removing investment limits for accredited investors. The temporary measures the commission introduced in May amid the economic crisis in the U.S. will be extended for 18 months, allowing firms that raise up to $250,000 over 12 months to qualify for an exemption.

Other modifications to the SEC framework include regulations on communications. The commission voted to allow regulation crowdfunding issuers and securities issuers to "test the waters" with the SEC to determine which exemption they would use for their sales, and ensure that communications from companies showcasing their securities offering "will not be deemed general solicitation or general advertising."

Under current regulations in the U.S., securities offerings — which include initial coin offerings — must either be registered with the SEC or qualify for an exemption. Many entrepreneurs, emerging businesses, and experienced securities issuers raise capital using the exempt-offering framework.

The SEC has seemingly taken a "regulation through enforcement" approach toward many crypto projects that it believes have broken existing regulations around unregistered securities. The department's case against Telegram resulted in the company abandoning its planned open network and linked Gram tokens, which had previously raised $1.7 billion.

The regulatory body first proposed simplifying the existing framework in June 2019 and announced in March that it had voted on a proposition to introduce the set of rule changes. According to the SEC, the majority of the amendments will be effective 60 days after publication in the Federal Register.

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Original article posted on the CoinTelegraph.com site, by Turner Wright.

Article re-posted on Markethive by Jeffrey Sloe

Bitcoin Pullback As US Presidential Elections Loom Could Ignite Meteoric Altcoin Upsurge: Analyst

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Bitcoin Pullback As U.S. Presidential Elections Loom Could Ignite Meteoric Altcoin Upsurge: Analyst

By Brenda Ngari – November 2, 2020

The Trump-Biden White House race is about to come to a close in a few days. Interestingly, bitcoin has been incredibly strong and resilient heading into the U.S presidential elections amid the stock market instability.

Last week, bitcoin came close to its June 2019 high above $13,800 and slumped as traditional markets crushed following mounting concerns about the sharp rise in COVID-19 cases. Bitcoin was, however, able to avoid a breakdown below $13,000 even as risk-off assets such as gold dropped to one-month lows. 

Surprisingly, bitcoin recovered and surged to $14,045 over the past weekend. This marked the highest level since January of 2018. Perhaps even more interesting, bitcoin breaching the $14K mark coincided with the 12-year anniversary since bitcoin creator Satoshi Nakamoto released the whitepaper on October 31, 2018.

However, the rally to $14,000 was met with violent rejection. One crypto analyst observed that the top cryptocurrency has put in a temporary top around this price level. The analyst expects continued weakness as the U.S. elections draw closer. This, according to him, will give altcoins enough momentum to shine as they post significant gains against the dominant cryptocurrency.

The analyst specifically said:

“I think bitcoin is putting in a temporary top. Price action to the upside when futures are closed gives me further indication that we’ll see a continued pullback into the election. Hopefully, after we’ll see capital go into alts. $eth $btc $link.”

In recent weeks, the altcoin market has seriously underperformed bitcoin. As such, it remains to be seen which catalyst will ignite a rotation of capital from the top crypto to the altcoins.

Notably, the growth of the decentralized finance (DeFi) industry has slowed down during the recent bitcoin mania. This implies that the sector could reawaken when altcoins start rallying massively.

On the other hand, there is a high possibility of a contested election and this could create uncertainty. Such uncertainty could start the next major Bitcoin market decline. Other analysts believe this may have a detrimental impact on altcoins.

At press time, bitcoin has lost 1.62% on the day to trade at $13,460.15.

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DISCLAIMER

The views expressed in the article are wholly those of the author and do not represent those of, nor should they be attributed to, ZyCrypto. This article is not meant to give financial advice. Please carry out your own research before investing in any of the various cryptocurrencies available.

The original article written by Brenda Ngari and posted on ZyCrypto.com.

Article reposted on Markethive by Jeffrey Sloe